Postdoc Position Computational Systems Biology

Systems Bioinformatics: Computational Modelling Methods, VU University Amsterdam, the Netherlands

Research project

The goal of the project is to develop and implement computer methods for computational modelling of biological systems. This encompasses methods for computational model assembly, execution, analysis and parameter estimation. This means collaboration with several experimental groups which work among others on metabolism in micro-organisms, animals and humans, on plant biology, nutrition and disease processes such as cancer. We also interact with the mathematical modelling group of the Netherlands Institute for Systems Biology. In this way this project is part of the core activity in Dutch systems biology.

The project focuses on developing and implementing computational methods generically useful for computational modelling of biological systems. This encompasses computational model assembly, modification, maintenance, execution, simulation, optimisation, parameter estimation etc. Parameter sensitivity spectrum analysis, ensemble simulation, model-based data analysis techniques, multiscale modelling, ‘e-BioScience’ approaches and data assimilation methods may be part of the project. Demonstration of the effectiveness of developed methods by application to modelling of some of the example biological systems is desirable.

This Systems Bioinformatics project is funded by The Netherlands Consortium for Systems Biology (NCSB) and in total involves six Dutch bioinformatics centres. In addition, the Systems Bioinformatics group is part of the BioAssist programme of the Netherlands Bioinformatics Centre. The VU group coordinates the six centres involved in the Systems Bioinformatics project. The Postdoc plays an active role in coordination of the project with the bioinformatic and experimental partners.

Further information:

http://www.vu.nl/nl/werken-bij-de-vu/vacatures/1-2008-00278.asp